PKRRATING OPTIONS

3B). R526 within the loop between αJ and αI anchors the C-terminal part of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the principle chain carbonyl of R413. The suggestion of the activation segment is stabilized by a hydrogen bond involving Y454 and E480 from α

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